PyOpenCL lets you access the OpenCL parallel computation API from Python. Here's what sets PyOpenCL apart:
See the PyOpenCL Documentation.
Having trouble with PyOpenCL? First, you may want to check the PyOpenCL Wiki. If that doesn't help, maybe the nice people on the PyOpenCL mailing list can.
Or get it directly from my source code repository by typing
git clone http://git.tiker.net/trees/pyopencl.git
You may also browse the source.
Prerequisites:
This past week, I had the honor of presenting a talk on PyCUDA at Nvidia's inaugural GPU Technology Conference.

Please click the following link to view the slides: pycuda-nvidia.pdf.
Update: Nvidia has posted a recording of the session that you may watch or download.